Are we ordering CAGG wisely? An audit of cold agglutinin requests and a rational testing algorithm

Key Points

• This research aims to evaluate the appropriateness of cold agglutinin requests and the effectiveness of current testing practices.
• Conducted an audit of cold agglutinin requests
• Reviewed completeness of haemolytic screens performed prior to testing
• Developed a rational testing algorithm based on findings.
• Found low diagnostic yield for cold agglutinin requests
• Identified significant number of requests made without complete haemolytic assessment
• Recommended a new testing algorithm to improve diagnostic efficiency.