Establishing basophil activation testing for routine drug allergy testing

Abigail Vallejo; Megan Yu; Jocelyn Jiang; Karl Baumgart

doi:10.1016/j.pathol.2026.01.297

February 1, 2026Pathology

Establishing basophil activation testing for routine drug allergy testing

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Key Points

To evaluate the effectiveness of basophil activation testing in diagnosing drug allergies, particularly when other methods are inconclusive.
Examined a commercial assay for basophil activation testing.
Assessed its utility in a routine drug allergy service.
Focused on cases where medication allergy was suspected.
Basophil activation testing demonstrated promise for antibiotic allergy diagnosis.
Improved accuracy observed in allergy diagnostics when traditional methods were inconclusive.

Implication

Analysis reveals basophil activation testing improves drug allergy diagnosis accuracy, suggesting utility in routine testing.

Abstract

Introduction: Basophil activation testing (BAT) shows promise for supporting antibiotic allergy diagnosis, when history is unclear or skin testing is inconclusive. We examined the utility of a commercial assay for a routine drug allergy service when medication allergy is suspected.

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Cite This Study

Vallejo et al. (2026) studied this question.

synapsesocial.com/papers/699a534bfdaf4e3c1268ee5c https://doi.org/10.1016/j.pathol.2026.01.297

View Full Paper

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Establishing basophil activation testing for routine drug allergy testing

Key Points

Implication

Abstract

Discussion

Cite This Study

Establishing basophil activation testing for routine drug allergy testing

Key Points

Implication

Abstract

Discussion

Cite This Study

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