Analysis compares kappa light chain levels in plasma cell dyscrasias using Freelite and N-Latex assays.
Background: Serum free light chain testing incorporating kappa (κ), lambda (λ) and the involved:uninvolved ratio (rFLC) underpins diagnosis and risk stratification in plasma cell dyscrasias. As clinical cut-offs are derived from the Freelite assay and New South Wales (NSW) laboratories now use N-latex, a comparison is required to guide clinical interpretation.
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Kwan et al. (2026) studied this question.
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