Ischemic intestinal manifestation of thromboangiitis obliterans (Buerger’s disease): a case report

Thromboangiitis Obliterans, or Buerger’s disease, is a non-atherosclerotic inflammatory vascular disease that most typically affects peripheral vasculature. 1 The condition is strongly associated with young male smokers, with links to non-tobacco smoking not yet established in literature. 2 Rare manifestations of the condition include intestinal involvement, manifesting as clinical intestinal ischemia. 1 From a histopathological assessment, Buerger’s disease classically demonstrates an occlusive, inflammatory thrombus with associated transmural vessel inflammation. 3 This pathology case report concerns a male patient in their 50s presenting with mesenteric ischemia on a background of Buerger’s disease, smoking, and methamphetamine use.