Case series identifies metaplastic breast carcinoma with osteoclast-like giant cells, suggesting a rare differential diagnosis.
Background : Metaplastic breast carcinomas (MBC) show differentiation of the neoplastic epithelium towards squamous or mesenchymal-looking elements, often presenting in older patients and at a higher stage. We present three cases further defined by a population of osteoclast-like giant cells (OCLGC), a rare entity that expands the list of differentials. 1,2
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