What question did this study set out to answer?

The research investigates lipidogram alterations in patients with Graves’ and Basedow’s disease, focusing on those with thyroid orbitopathy.

February 22, 2026Endokrynologia Polska0 citationsOpen Access

Lipidogram profiles in patients with Graves’ and Basedow’s disease with and without orbitopathy

MNMariusz NowakMedical University of Silesia WNWojciech NowakMedical University of Silesia MLMagdalena Londzin-OlesikMedical University of Silesia

Key Points

The research investigates lipidogram alterations in patients with Graves’ and Basedow’s disease, focusing on those with thyroid orbitopathy.
Analyzed lipid profiles in patients with Graves’ and Basedow’s disease.
Compared lipid levels in patients with and without thyroid orbitopathy.
Examined the impact of statin therapy during treatment.
Increased total cholesterol (TC) and LDL-C levels observed in patients on treatment.
Elevated Apo B levels identified during treatment.
Statins showed potential anti-inflammatory effects in this patient population.

Abstract

The use of statins as adjunctive therapy in GBD patients with active TO qualified for immunosuppressive treatment is reasonable due to the increase in TC, LDL-C, and Apo B levels during treatment, as well as for their pleiotropic effects, including their anti-inflammatory effects.

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