Heterotopic ossification of the abdominal cavity in a patient with complicated Crohn’s disease

Heterotopic ossification (HO) is a metaplastic phenomenon in which components of mature lamellar bone form outside skeletal tissue. Foci of ossification in this phenomenon occur in the skin, scar tissue, subcutaneous fat, muscle tissue of limbs, mesenteric tissues. Formation of bone fragments in the mesentery (heterotopic mesenteric ossification (HMO)) is considered a very rare phenomenon: 75 clinical cases have been described in abdominal surgery up to 2022. As a rule, HMO occurs in adult male patients with recurrent abdominal injuries (the ratio of cases in men and women is 10:1), the average age is 58.28±18.27 years. Cases of HMOs with the development of hematopoiesis foci are even rarer. For today, according to available literature sources, there are a few cases in the world of HMOs with the development of hematopoiesis in the focus of ossification. There are also two clinical cases of GMO development in patients with IBD described in the world medical literature. In this article, we report on the clinical case of HMOs with the development of a focus of bone marrow hematopoiesis in a 56-year-old man with Crohn’s disease complicated by surgical pathology, for which the patient underwent a series of surgical interventions with the formation of an obstructive ileostomy, which is the world’s third case of GMO development in a patient with IBD.