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February 22, 2026International Journal of NanomedicineOpen Access

Surface-Engineered Precision Nano-Systems for Targeted Treatment of Huntington’s Disease: A Review of Recent Advancements

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Authors

JZJingze ZhangLNLili NieJMJingru Ma

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Overview

This review highlights advancements in nanosystems for targeted treatment of Huntington’s disease, suggesting a transformative approach to therapy.

Key Points

  • This review examines innovative nanosystems aimed at targeted treatment for Huntington's disease.
  • Reviewed recent advancements in surface-engineered nanosystems
  • Analyzed different types of nanosystems including liposomes and dendrimers
  • Discussed mechanisms for overcoming the blood-brain barrier
  • Explored therapeutic and diagnostic applications of nanoparticles
  • Nanosystems can deliver therapeutic agents directly to brain regions affected by Huntington's disease
  • Targeted approach enhances treatment efficacy and reduces side effects
  • Identified challenges like safety assessments and FDA approval for new nanoparticles

Cite This Study

Zhang et al. (2026) studied this question.

synapsesocial.com/papers/699a9d7a482488d673cd3666https://doi.org/10.2147/ijn.s548892
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