Key result
Leadless pacemakers show lower device-related complication rates versus transvenous pacemakers alongside longer battery life.
Why the study?
Over the past decade, leadless pacing has evolved rapidly with multiple devices offering technological advancements and lower complication rates than transvenous pacemakers, warranting an overview of its clinical landscape.
Leadless pacemakers are rapidly evolving to offer lower complication rates and advanced pacing modes, with future potential for integration with subcutaneous ICDs and conduction system pacing.
May inform device selection in select patients; leaves open need for randomized confirmation before broader adoption.
Over the past decade, leadless pacing has undergone a rapid evolution, resulting in multiple leadless pacemaker (LPM) devices that offer advancements such as atrioventricular synchronized pacing in VDD mode, atrial stimulation, dual-chamber pacing, and longer battery longevity. Studies comparing LPMs with transvenous pacemakers (TVPMs) show a lower rate of device-related complications with LPMs. In the near future, LPMs could be combined with other devices such as non-transvenous implantable cardioverter-defibrillators to provide anti-tachycardia pacing or bradycardia pacing. Future prospectives for leadless cardiac resynchronization therapy and leadless conduction system pacing are being investigated. As LPMs continue to improve, their applications are anticipated to expand further improving patient outcome, promising a bright future for leadless pacing. In this review, the past, present, and future of leadless pacing are discussed with a focus on cutting-edge implantation techniques, clinical outcomes, and modern advancements of LPMs.
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Saleem-Talib et al. (2025) studied this question. Leadless pacemakers show lower device-related complication rates than transvenous pacemakers and offer advancements like VDD mode and longer battery life.
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