Fluorescent Aptasensor for Enrofloxacin Detection based on APE1 Assisted Amplification and CsPbBr 3 @MSN Nanocomposites

Huanhuan He; Jing Feng; Luna Guo; Weiling Song; Hong Zhen Zhou

doi:10.1039/d6an00085a

January 1, 2026The Analyst

Fluorescent Aptasensor for Enrofloxacin Detection based on APE1 Assisted Amplification and CsPbBr 3 @MSN Nanocomposites

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Key Points

To develop a sensitive fluorescent aptasensor for detecting enrofloxacin using APE1 amplification.
Constructed a fluorescent aptasensor using polyvalent aptamers and APE1 for signal amplification.
Utilized CsPbBr3 at mesoporous silica nanoparticles to enhance detection sensitivity.
Employed fluorescence techniques to measure enrofloxacin levels.
The aptasensor showed high sensitivity for enrofloxacin detection.
Successful amplification of the signal was observed with APE1.
Detection limits for enrofloxacin were significantly improved compared to conventional methods.

Implication

Fluorescent aptasensor detects enrofloxacin, indicating potential for rapid antibiotic testing.

Abstract

In this work, a fluorescent aptasensor was constructed for enrofloxacin (ENR) detection by combining with the polyvalent aptamers (PAs) structure, apurinic/apyrimidinic endonuclease 1 (APE1) mediated signal amplification and mesoporous silica...

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Cite This Study

He et al. (2026) studied this question.

synapsesocial.com/papers/699a9de0482488d673cd413e https://doi.org/10.1039/d6an00085a

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Fluorescent Aptasensor for Enrofloxacin Detection based on APE1 Assisted Amplification and CsPbBr 3 @MSN Nanocomposites

Key Points

Implication

Abstract

Discussion

Cite This Study

Fluorescent Aptasensor for Enrofloxacin Detection based on APE1 Assisted Amplification and CsPbBr 3 @MSN Nanocomposites

Key Points

Implication

Abstract

Discussion

Cite This Study

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