What question did this study set out to answer?

The aim is to highlight early signs of hydroxychloroquine toxicity in retinal imaging.

February 22, 2026Parul University Journal of Health Sciences and Research

A Subtle Case of Hydroxychloroquine Maculopathy: Early Changes on Spectral-domain-ocular Coherence Tomography

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Case report evaluates hydroxychloroquine toxicity effects on retinal structure, suggesting early detection is crucial.

The aim is to highlight early signs of hydroxychloroquine toxicity in retinal imaging.
Case report detailing a 54-year-old female with rheumatoid arthritis.
Optical coherence tomography used to assess retinal layers.
Observation of macula changes related to hydroxychloroquine toxicity.
Subtle thinning of the outer nuclear layer observed in both eyes.
Disruption of the ellipsoid zone and preservation of the central fovea noted.
Early signs consistent with hydroxychloroquine retinopathy were identified.

Nayak et al. (2025) studied this question.

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