What type of study is this?

This is a Cross-Sectional Study study.

What question did this study set out to answer?

This research aims to assess the role of non-serogroup 1 L. pneumophila in hospital-acquired pneumonia (HAP).

February 23, 2026Lung India1 citationsOpen Access

Detection of L. pneumophila non-serogroup 1 in hospital-acquired pneumonia: A cross-sectional study from Eastern India

MSM. L. SivalekshmiAll India Institute of Medical Sciences Bhubaneswar SRSutapa RathAll India Institute of Medical Sciences Bhubaneswar KGKrishna M. GullaAll India Institute of Medical Sciences Bhubaneswar

Key Points

This research aims to assess the role of non-serogroup 1 L. pneumophila in hospital-acquired pneumonia (HAP).
Conducted a cross-sectional study in Eastern India.
Utilized PCR to detect L. pneumophila non-serogroup 1.
Analyzed hospital-acquired pneumonia cases confirmed by microbiology.
Identified L. pneumophila non-serogroup 1 in 12.5% of microbiologically confirmed HAP cases.
PCR tests detected pathogens that were missed by culture and urinary antigen testing.
Highlights the necessity of integrating Lp molecular tests in diagnostic protocols for HAP cases.

Abstract

This study highlights the significant role of Lp non serogroup 1 as a pathogen in 12.5% of microbiologically confirmed HAP cases, using PCR, which were negative by culture and commercially available urinary antigen testing targeting Lp serogroup 1. The findings emphasize incorporating Lp molecular tests along with Ag testing in the diagnostic algorithm of HAP cases.

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