Spermidine improve high copper diet -induced intestinal oxidative stress and microbiota community composition

Key Points

• The aim is to investigate how spermidine affects oxidative stress and microbiota in response to high copper diets.
• Experimental design examining the impact of spermidine on high copper diet subjects
• Assessment of intestinal oxidative stress levels and microbiota composition
• Evaluation of antioxidant markers and immune function
• Spermidine supplementation reduces oxidative stress levels
• Alters microbiota composition by enhancing Lachnospiraceae
• Boosts immune function markers such as IgA