What question did this study set out to answer?

To assess the rates of diabetes-related complications and the direct medical costs associated with severe hypoglycemia in individuals with type 1 diabetes.

February 23, 2026Advances in Therapy0 citationsOpen Access

Hospital-Treated Severe Hypoglycemia in Type 1 Diabetes in the US: A Retrospective Claims-Based Study of Diabetes-Related Complications and Direct Medical Costs

ABAdriana Boateng-KuffourVertex Pharmaceuticals (United States)NLNanxin LiVertex Pharmaceuticals (United States)KCKeval ChandaranaVertex Pharmaceuticals (United States)

Key Points

To assess the rates of diabetes-related complications and the direct medical costs associated with severe hypoglycemia in individuals with type 1 diabetes.
Conducted a retrospective claims-based analysis
Identified patients with type 1 diabetes experiencing hospital-treated severe hypoglycemia
Evaluated diabetes-related complications and associated medical costs
Identified high rates of diabetes-related complications in severe hypoglycemia cases
Observed elevated direct medical costs for hospital-treated severe hypoglycemia
Highlighted the complexity of managing type 1 diabetes in these cases

Abstract

High T1D-related complication rates and elevated direct medical costs highlight the complexity of pwT1D who experienced hospital-treated SHEs.

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