Stability study of medical peracetic acid during using period

ObjectiveTo measure the content changes of different brands of peracetic acid (PAA) disinfectants under different conditions of use, and to provide data for stability test of peracetic acid.MethodsThe contents of nine brands of PAA disinfectants after single-use opening, daily opening for one hour, daily sampling and dilution, and daily on-site endoscopic decontamination were measured. Moreover, the PAA contents in three brands of disinfectants were determined after the use cycle was extended to 28 days.ResultsThe PAA disinfectants were tested after single-use opening, daily opening for one hour, or daily sampling and dilution. The PAA concentrations in two to three of the nine brands of disinfectants were reduced to less than 1.00 g/L. After daily endoscopic decontamination, the reduction rate of PAA was higher than that of other usage patterns. In this experiment, one PAA disinfectant had good stability, with a content of >1.50 g/L until Day 28.ConclusionThe endoscopic decontaminator is suitable for evaluating the stability of PAA after continuous use. Moreover, the stability of different PAA disinfectants varies greatly, and some disinfectants may not be able to maintain a qualified effective concentration of PAA for continuous use.