Abstract Globally, pancreatic cancer continues to be a significant health problem. The number of new cases has been increasing by an average of 0.8% per year over the last decade. The prognosis remains extremely poor, with a five-year survival rate of 7.2%, confirming its reputation as one of the deadliest malignant diseases. Objective to ana-lyze recent developments in the management of the diagnostic and treatment process for pancreatic cancer. Materials and Methods systematic review of scientific publications through documentary analysis and analysis of the content of scientific publications selected by predefined key words. Results and Discussion pancreatic cancer is one of the greatest clinical challenges in modern oncology, characterized by an extremely high mortality rate. Due to the lack of specific early manifestations and the biological aggressiveness of the disease, diagnosis is delayed in more than 80% of cases. Pancreatic disease should always be considered in the differential diagnosis of any acute or chronic pain. Successful management of these complex tumors requires a nuanced, multidisciplinary approach that integrates precise diagnosis, staging, and individualized therapeutic strategies.
Angelov et al. (Sun,) studied this question.