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February 25, 2026Cardiology in the Young0 citations

Individualised interventional strategies and clinical outcomes in paediatric patients with pulmonary arterial hypertension

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ETEmine Gülşah TorunODOğuzhan DoğanDBDenizhan Bağrul

Key Points

  • To evaluate the impact of individualised interventional strategies on clinical outcomes in paediatric patients with pulmonary arterial hypertension.
  • Conducted comprehensive haemodynamic assessments
  • Implemented partial ASD closure as an interventional strategy
  • Monitored clinical outcomes and quality of life metrics
  • Assessed the effects on mortality and disease progression
  • Individualised strategies slowed disease progression
  • Improved quality of life reported in patients
  • Partial ASD closure led to reduced volume load and enhanced haemodynamic stability
  • Timely interventions associated with decreased mortality risk

Abstract

Individualised interventional strategies guided by comprehensive haemodynamic assessment can slow disease progression and improve quality of life in paediatric pulmonary arterial hypertension. Partial ASD closure, as a novel approach in this cohort, reduces excessive left-to-right volume load while preserving a controlled right-to-left shunt, thereby enhancing haemodynamic stability and optimising outcomes. Timely implementation of interventional strategies before disease progression may help reduce mortality.

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Cite This Study

Torun et al. (2026) studied this question.

synapsesocial.com/papers/699e912ef5123be5ed04e84bhttps://doi.org/10.1017/s104795112611141x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Fenestrated Occluders for Treatment of ASD in Elderly Patients with Pulmonary Hypertension and/or Right Heart Failure2007 · 41 citations
  2. 22022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension2022 · 3,891 citations
  3. 3Role of atrial septostomy in the treatment of pulmonary vascular disease2000 · 53 citations
  4. 4Study of the effect of Occlutech Atrial Flow Regulator on symptoms, hemodynamics, and echocardiographic parameters in advanced pulmonary arterial hypertension2021 · 33 citations
  5. 5Fenestrated Transcatheter ASD Closure in Adults with Diastolic Dysfunction and/or Pulmonary Hypertension: Case Series and Review of the Literature2016 · 57 citations