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February 25, 2026CancersOpen Access

Predictors of Pre- and Postoperative Quality of Life and Overall Survival in Patients with Non-Small Cell Lung Cancer: A Prospective Study

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Authors

RFRyuta FukaiTNTomoki NishidaNYNobuo Yamaguchi

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Overview

Prospective study evaluates HR-QOL and survival in lung cancer patients, suggesting influential socioclinical factors.

Key Points

  • This study evaluates how certain factors impact quality of life and survival for lung cancer patients undergoing surgery.
  • Conducted a prospective study with 87 patients at Shonan Kamakura General Hospital.
  • Analyzed HR-QOL using Short Form Health Survey 36 preoperatively and at 6 months postoperatively.
  • Performed multivariable and survival analyses to identify significant predictors of HR-QOL and survival.
  • Lower performance status and living alone correlated with worse physical and mental QOL before surgery.
  • Smoking cessation, lower performance status, and living alone predicted poorer physical quality of life at 6 months after surgery.
  • Higher comorbidity burden and lower performance status were linked to poorer long-term survival.

Cite This Study

Fukai et al. (2026) studied this question.

synapsesocial.com/papers/699e9152f5123be5ed04eca0https://doi.org/10.3390/cancers18040714
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