Systematic review compares ventilatory support efficacy in children with asthma exacerbation, suggesting implications for treatment choices.
Both HFNC and BiPAP can provide adequate ventilatory support for children with asthma exacerbation. In the subset of studies reporting oxygenation outcomes (2-3 studies), BiPAP was associated with a small increase in PaO₂/SaO₂ compared with HFNC; this limited signal requires confirmation in larger, high-quality clinical trials.
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Cheng et al. (2026) studied this question.
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