Case report investigates systemic absorption effects of biliary contrast in a male with biliary stricture, suggesting individual variability in absorption rates.
A 21-year-old male with primary sclerosing cholangitis was submitted to a lengthy endoscopic retrograde cholangiopancreatography (ERCP) for evaluation and treatment of a relevant biliary stricture causing obstructive cholestasis. At first (Fig. 1), a cholangiogram was produced using radiopaque contrast. Toward the end of the uneventful procedure (Fig. 2), a contrast pyelogram became progressively more evident. Although systemic absorption of contrast during ERCP is well documented, it is thought to be significantly lower compared to other contrast-dependant exams [1], [2], [3]. However, it is important to consider individual variability, since some patients may have higher systemic absorption, particularly with longer procedures [1].
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Damasceno et al. (2026) studied this question.
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