Findings show that urine cultures are unnecessary for most low-risk febrile infants, suggesting a more targeted approach to testing.
Clinically relevant UTIs are rare in febrile infants < 3 months of age without risk factors and with negative urine dipsticks. Urine cultures should not be obtained in all febrile infants with fever but should be reserved for those with an indication of UTI or serious bacterial infection.
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Sjöstedt et al. (2026) studied this question.
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