What does this research mean for the field?

Metastatic cutaneous squamous cell carcinoma occurs predominantly in elderly patients, with a high mortality rate and a median overall survival of 56% at 2 years. Novelty: ClaimNovelty.CONFIRMATORY. Consensus alignment: ConsensusAlignment.SUPPORTS_CONSENSUS.

What question did this study set out to answer?

To examine the characteristics and outcomes of patients with metastatic cutaneous squamous cell carcinoma in Sweden.

February 25, 2026Acta Dermato VenereologicaOpen Access

Poor Outcome of Metastatic Cutaneous Squamous Cell Carcinoma: A Swedish Retrospective Study

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To examine the characteristics and outcomes of patients with metastatic cutaneous squamous cell carcinoma in Sweden.
Retrospective review of 137 patients with metastatic cutaneous squamous cell carcinoma
Patient data collected from the Stockholm region from 2012-2020
Analysis included primary tumour characteristics, patient demographics, treatments, and outcomes.
Median overall survival at 2 years was 56%
90% of metastases diagnosed within 2 years of primary tumour diagnosis
50% of primary tumours classified as high-risk according to established criteria.
Most patients treated with surgery and radiotherapy

Discussion

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Implication

This retrospective study highlights poor outcomes in elderly patients with metastatic cutaneous squamous cell carcinoma, indicating challenges in early identification of high-risk tumours.

Cite This Study

Palmqvist et al. (2026) studied this question.

synapsesocial.com/papers/699e91fdf5123be5ed04fdce https://doi.org/10.2340/actadv.v106.44057

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Implication

This retrospective study highlights poor outcomes in elderly patients with metastatic cutaneous squamous cell carcinoma, indicating challenges in early identification of high-risk tumours.

Poor Outcome of Metastatic Cutaneous Squamous Cell Carcinoma: A Swedish Retrospective Study

Key Points

Discussion

Implication

Cite This Study

Poor Outcome of Metastatic Cutaneous Squamous Cell Carcinoma: A Swedish Retrospective Study

Key Points

Discussion

Implication

Cite This Study

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