Prospective clinical study reports effective treatment outcomes in Dientamoeba fragilis infection, suggesting important management strategies.
DF should be considered in patients with unexplained chronic gastrointestinal symptoms. Molecular testing is recommended for accurate diagnosis. Paromomycin appears to be the most effective treatment, with a strong association between clinical recovery and microbiological cure. Randomized controlled trials are warranted to further define optimal management strategies for DF infection.
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Biber et al. (2026) studied this question.
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