What question did this study set out to answer?

This study aims to explore how different breathing frequencies affect respiratory oscillometry measurements in asthma patients.

February 25, 2026BMJ Open Respiratory ResearchOpen Access

Impact of breathing frequency on respiratory oscillometry measurements: a randomised cross-over and observational study of asthma patients

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Authors

BKBen Knox-BrownCambridge University Hospitals NHS Foundation Trust OCOlga CarozzoCambridge University Hospitals NHS Foundation Trust KSKarl P SylvesterCambridge University Hospitals NHS Foundation Trust

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Implication

A randomized crossover study investigates how varying breathing rates affect respiratory measurements in asthma patients, suggesting controlled breathing rates for accuracy.

Key Points

This study aims to explore how different breathing frequencies affect respiratory oscillometry measurements in asthma patients.
Participants performed the forced oscillation technique at different controlled breathing frequencies (15, 30, 40 bpm) using a metronome.
A randomised crossover design was employed, ensuring each participant experienced all breathing frequencies.
Analysis of variance (ANOVA) and Friedman tests assessed the significance of differences in measurements.
Total airway resistance (Rrs at 5 Hz) decreased significantly by 8.6% when breathing frequency increased from 15 bpm to 40 bpm (p<0.001).
Delta R5-R19 showed a significant reduction of 14.9% (p<0.001), and reactance (Xrs at 5 Hz) increased by 10.9% (p=0.081).
At higher breathing frequencies, 5% of participants' measurements were reclassified as normal.

Cite This Study

Knox-Brown et al. (2026) studied this question.

synapsesocial.com/papers/699e91fdf5123be5ed04feed https://doi.org/10.1136/bmjresp-2025-003657

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Implication

A randomized crossover study investigates how varying breathing rates affect respiratory measurements in asthma patients, suggesting controlled breathing rates for accuracy.

Impact of breathing frequency on respiratory oscillometry measurements: a randomised cross-over and observational study of asthma patients

Discussion

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Implication

Key Points

Cite This Study

Impact of breathing frequency on respiratory oscillometry measurements: a randomised cross-over and observational study of asthma patients

Discussion

Member takes

Implication

Key Points

Cite This Study

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