This research demonstrates a new method to enhance mechanosensing using hydrogels with a birefringence-stress reader, suggesting improved sensor technology.
We present a strategy to program hydrogel photoelasticity using rationally designed force-transducing crosslinkers. Enabled by a simultaneous birefringence-stress reader (SiBRe), we show that stress-induced unfolding of flexible linkers can amplify the optical response, establishing a robust, dye-free platform for quantitative mechanosensing.
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Katsuki et al. (2026) studied this question.
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