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Simultaneous optimization of assembly time and yield in programmable self-assembly

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Simulation reveals design optimization enhances assembly speed and yield in self-assembly systems, suggesting key strategies.

To explore the optimization of assembly time and yield in programmable self-assembly systems.
Formulated assembly as a complex reaction network.
Calculated tradeoff between assembly speed and quality.
Optimized binding energies and particle concentrations.
Achieved significant speedups in assembly time without reducing yield.
Identified parameter optimization as crucial for enhancing self-assembly performance.
Demonstrated advantages of semi-addressable systems in assembly efficiency.

Hübl et al. (2026) studied this question.

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