What type of study is this?

This is a Meta-Analysis study (also classified as: Systematic Review).

What question did this study set out to answer?

This review evaluates the antidepressant effects of icariin in rodent models of depression and anxiety.

View Full Paper

Ask AI

Bookmark

Authors

Systematic review reveals icariin reduces symptoms of depression in rodent models, highlighting its neuroprotective potential.

This review evaluates the antidepressant effects of icariin in rodent models of depression and anxiety.
Conducted a systematic review and meta-analysis.
Included 23 preclinical studies, with 13 providing data for meta-analysis.
Literature searches were performed in Scopus, PubMed, and Embase following PRISMA 2020 guidelines.
Icariin significantly improved anhedonia-like behavior with a pooled Hedges’ g of 2.26.
Markedly reduced immobility in the forced swim test with a pooled Hedges’ g of 3.64.
Evidence suggests icariin works through enhancing neuroplasticity and inhibiting neuroinflammation.

He et al. (2026) studied this question.

View Full Paper

Ask AI

Bookmark