Recent findings show that SARS-CoV-2 mRNA vaccination boosts cancer survival with immune therapies, suggesting broad vaccine utility.
A recent paper in Nature shows that SARS-CoV-2 mRNA vaccination within 100 days of beginning immune checkpoint inhibitor immunotherapy improves survival of cancer patients by systemically inducing Type I interferons, suggesting that an off-the-shelf cancer vaccine that potently stimulates innate immunity may not need to be customized to contain tumor-associated antigens to be effective.
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Yisimayi et al. (2026) studied this question.
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