Life-threatening intraparenchymal hematoma due to immune thrombocytopenic purpura: illustrative case.

This case highlights critical lessons in the management of IPH secondary to ITP. In the event of life-threatening IPH, emergency craniotomy and hematoma evacuation are necessary. Platelet support is achieved through transfusion, IVIG, and steroids. Splenectomy should be performed as soon as feasible following the evacuation of a hematoma to prevent the recurrence of thrombocytopenia, which may result in rebleeding. Collaboration among neurosurgeons, hematologists, and intensivists is key to a satisfactory outcome. https://thejns.org/doi/10.3171/CASE25394.