Pai Syndrome

Pai Syndrome A full-term male infant was referred to maxillofacial surgery for a diagnosis of feeding disorder due to orofacial polyps. The newborn male was healthy with no significant medical history and no family history of the same symptoms. Clinical examination revealed that he had a 1.5cm well-circumscribed mass on the labial surface of the central incisor area, multiple facial skin polyps on the nose, and an incomplete alveolar cleft in the midline (Panel A). Under local anesthesia, laser ablation of orofacial masses at 1.7W; CM; 980nm Biolase. The diagnosis was confirmed by histopathological examination of the resected mass, and excellent healing was achieved (Panels B and C). Pai syndrome is a rare disease that was first described in 1987. Diagnostic criteria are the presence of nasal polyps and one of the following symptoms: median cleft lip, congenital mid-alveolar process polyp, and pericallosal lipoma. However, few patients exhibit the complete triad, and most patients exhibit a wide range of phenotypic variation. However, only 17 of these cases met the classic clinical triad. Although the etiology of Pai syndrome is unknown, cosmetic and functional recovery of malar and nasal abnormalities is possible, and the prognosis for most patients is good. Laser surgery has the proven benefit of reducing postoperative pain and improving surgeon comfort by eliminating intraoperative bleeding and reducing the risk of recurrence.