Retrospective analysis demonstrates higher recurrence and metastasis risk in poorly differentiated cSCC, suggesting need for tailored surveillance.
Deeper growing, poorly differentiated cSCC tumors of the head and neck carry a higher risk of recurrence and metastasis. Pursuing greater deep excision margins could reduce these risks. Given the high age and all-cause mortality rates of cSCC patients, close surveillance should be individualized.
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Korhonen et al. (2026) studied this question.
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