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February 27, 2026European journal of medical researchOpen Access

Differences in the profile of mild cognitive impairment among inpatients with T2DM: a comparison of the MMSE and MoCA

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Authors

YLYamin LiuCentral South UniversityRMRehanguli MaimaitituerxunNanjing Municipal Center for Disease Control And PreventionWCWenhang ChenCentral South University

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Implication

Cross-sectional study compares cognitive impairment assessment tools in T2DM inpatients, suggesting potential intervention targets.

Key Points

  • This research aims to evaluate differences in mild cognitive impairment profiles in T2DM inpatients using MMSE and MoCA assessments.
  • Conducted a cross-sectional study in a hospital setting among T2DM inpatients.
  • Collected demographic and clinical data through questionnaires and interviews.
  • Used MMSE and MoCA to identify mild cognitive impairment across participants.
  • Applied multivariate logistic regression to analyze factors associated with MCI.
  • Prevalence of MCI detected was 18.4% by MMSE and 51.9% by MoCA.
  • Found fair agreement between MMSE and MoCA with a kappa value of 0.287.
  • Age and diabetic nephropathy associated with MCI in both assessments.
  • MoCA proved to be more sensitive than MMSE for detecting MCI.

Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/69a134dded1d949a99abe48ahttps://doi.org/10.1186/s40001-026-04107-3
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