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This study aimed to evaluate the patterns in pharmacological management of orofacial pain and identify factors influencing treatment decisions.

February 27, 2026Open Access

Pharmacological management in orofacial pain: a retrospective, observational study of treatment decisions and contributing factors

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This study aimed to evaluate the patterns in pharmacological management of orofacial pain and identify factors influencing treatment decisions.
Analyzed patient files from the Orofacial Pain Unit at the University of Zurich.
Recorded demographics, pain characteristics, diagnoses, and pharmacotherapy before and after specialist consultation.
Conducted statistical analyses including descriptive statistics and chi-square tests.
208 patients included; mean age 45.9 years with a mean pain intensity of 6.93.
Pharmacological therapy usage increased from 51.4% to 74.5% post-consultation.
Topical NSAIDs (64.0%) and magnesium (40.0%) were the most prescribed treatments.
Positive therapy outcomes reported in 67.0% of patients.
Significant relationships found between diagnosis and therapy changes, particularly for myofascial pain.

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Observational study evaluates treatment choices in orofacial pain patients, indicating significant influences on therapy outcomes.

Mundackal et al. (2026) studied this question.

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