Key result
LBBAP appears safe and is linked to improved short-term electrical and mechanical synchronization in pediatric patients.
Why the study?
Does left bundle branch area pacing (LBBaP) provide safe and effective pacing in pediatric patients?
Observational (n=18)
Does left bundle branch area pacing (LBBaP) provide safe and effective pacing in pediatric patients?
Left bundle branch area pacing is a safe and effective alternative pacing strategy in pediatric patients, providing good electrical synchronization and stable pacing parameters at short-term follow-up.
Should not change pediatric pacing practice yet; leaves open long-term LBBaP safety and efficacy pending prospective trials.
Background Left bundle branch area pacing (LBBaP) is a recently emerged and widely adopted technique of cardiac physiological pacing. However, there is still limited data about LBBaP in children. Methods Eighteen patients who consecutively underwent permanent pacemaker (PPM) implantation via LBBaP were enrolled in this study. Periprocedural and postprocedural follow‐up data were retrospectively evaluated. Results The mean age was 12.3 ± 5.8 years (13 months–18 years). The mean body weight was 41.5 ± 21 kg (8–77 kg). PPM indications were congenital atrioventricular (AV) block in 13 (72%) and post‐interventional AV block in 5 (27%) children. On 10/18, patients (55%) had previously received PPMs implanted in the right ventricular apex or epicardial region. The mean left ventricular activation time (LVAT), the V 6 ‐V 1 inter‐peak delay, and the paced QRS duration were 61 ± 9 ms, 31 ± 13 ms, and 94 ± 13 ms, respectively. No complications were observed during the procedure and follow‐up. During the mean 13.5 ± 7.5 months of follow‐up, the mean ventricular lead impedance was 578 ± 90 ohms, and the pacing threshold was between 0.25 and 0.75 mV. Conclusion The LBBaP is an effective and safe alternative for pacing in pediatric patients at short‐term follow‐up. The LBBaP acts as an alternative pacing site in children, offering improved electrical and mechanical synchronization for those who need a high rate of ventricular pacing and have a longer life expectancy.
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Karagöz et al. (2026) conducted an observational in Pediatric patients requiring permanent pacemaker implantation (n=18). Left bundle branch area pacing (LBBaP) was evaluated on Complications during procedure and follow-up. Left bundle branch area pacing in pediatric patients resulted in 0% complications over a mean 13.5-month follow-up, with a mean paced QRS duration of 94 ms.
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