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This editorial examines the connection between the gut microbiome and gastric cancer, focusing on H. pylori and related microbial factors.

February 28, 2026Frontiers in MicrobiologyOpen Access

Editorial: The gut microbiome's role in gastric cancer: mechanisms and therapies

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This editorial examines the connection between the gut microbiome and gastric cancer, focusing on H. pylori and related microbial factors.
Identified microbial profiles associated with gastric cancer risk.
Discussed mechanisms by which H. pylori promotes gastric inflammation and neoplasia.
Evaluated therapeutic potentials of probiotics and antibiotics to limit gastric cancer.
H. pylori is a major contributor to gastric cancer risk in high-risk individuals.
Elimination of H. pylori can slow gastric cancer progression, but efficacy varies by cancer stage.
Certain non-H. pylori bacteria may influence cancer development and treatment responses.

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Editorial reveals mechanisms linking gut microbiome to gastric cancer, highlighting potential therapies for prevention.

Ağagündüz et al. (2026) studied this question.

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