SAr reaction explores heterocycle synthesis using 4,5-dichlorophthalonitrile, indicating potential reactions may yield mixtures or rearrangements.
The SAr reaction of 4,5-dichlorophthalonitrile with various bifunctional nucleophiles was carried out in anhydrous DMF in the presence of KCO as a deprotonating agent. It was shown that 4,5-dichlorophthalonitrile can be successfully employed in the synthesis of heterocyclic compounds; however, in some cases, these reactions may either give product mixtures or result in an unexpected rearrangement.
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V.L. Baklagin (2025) studied this question.
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