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February 28, 2026Journal of Clinical Medicine0 citationsOpen Access

Mental Health Challenges in Siblings of Anorexia Nervosa Patients: A Review

Psychopathology and Other Mental Health Challenges in Siblings of Patients with Child- or Adolescent-Onset Anorexia Nervosa: A Systematic Review with a Sex/Gender Perspective

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Authors

ETElisabet Tasa-VinyalsMPMaría Teresa PlanaAMAlbert Martínez-Pinteño

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Overview

A systematic review assesses psychiatric symptoms in siblings of anorexia nervosa patients, indicating an urgent need for inclusive studies.

Key Points

  • This review examines the prevalence of mental health challenges in siblings of patients with anorexia nervosa, focusing on sex/gender influences.
  • Conducted a systematic search following PRISMA guidelines across five databases.
  • Registered protocol in PROSPERO.
  • Reviewed sixteen studies published from 1983 to 2022.
  • Evaluated the quality and risk of bias of included studies from a sex/gender perspective.
  • Noted increased prevalence of internalizing and externalizing symptoms in siblings compared to controls.
  • Siblings generally more similar to controls than to affected patients in psychometric evaluations.
  • Clinically diagnosed psychopathology indicated increased risk of mental health disorders in siblings.
  • Study quality assessment revealed a systematic bias against externalizing symptoms and male siblings.
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Cite This Study

Tasa-Vinyals et al. (2026) studied this question.

synapsesocial.com/papers/69a286eb0a974eb0d3c02344https://doi.org/10.3390/jcm15051772
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