What question did this study set out to answer?

Investigate the role of Rabankyrin-5 in endosomal fusion during human papillomavirus entry.

The Rab5 effector Rabankyrin-5 mediates endosomal fusion and trafficking of human papillomavirus during early entry

View Full Paper

Ask AI

Bookmark

Authors

Reveals Rabankyrin-5 mediates endosomal fusion in human papillomavirus entry, indicating a role in viral infection mechanisms.

Investigate the role of Rabankyrin-5 in endosomal fusion during human papillomavirus entry.
Identified Rabankyrin-5 as a Rab5 effector involved in endosomal processes.
Examined its interaction with HPV minor capsid protein L2 and dynein motor complex.
Analyzed the impact of Rabankyrin-5 on endosomal fusion and virus transport along microtubules.
Rabankyrin-5 is essential for the fusion of HPV-carrying endosomes during entry.
It acts as a dynein adaptor, linking the HPV minor capsid protein L2 and dynein motor complex.
Facilitates virus movement along microtubules, supporting early viral entry.

Love et al. (2026) studied this question.

View Full Paper

Ask AI

Bookmark