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November 22, 2021European Heart Journal152 citationsOpen Access

Comparative effects of guided vs. potent P2Y12 inhibitor therapy in acute coronary syndrome: a network meta-analysis of 61 898 patients from 15 randomized trials

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MGMattía GalliSBStefano BenenatiFFFrancesco Franchi

Structured PICO

Does guided selection of P2Y12-inhibiting therapy improve the balance between safety and efficacy compared to potent P2Y12 inhibitor therapy in patients with acute coronary syndrome?

P
Population
61,898 patients with acute coronary syndrome (pooled from 15 randomized trials)
I
Intervention
Guided selection of P2Y12-inhibiting therapy
C
Comparator
Potent P2Y12 inhibitor therapy

Guided selection of P2Y12-inhibiting therapy offers the most favorable balance of safety and efficacy in patients with acute coronary syndrome, supporting its broader adoption.

Abstract

A guided selection of P2Y12-inhibiting therapy represents the strategy associated with the most favourable balance between safety and efficacy. These findings support a broader adoption of guided P2Y12 inhibiting therapy in patients with acute coronary syndrome.

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Cite This Study

Galli et al. (2021) studied this question.

synapsesocial.com/papers/69a303c214f6f437bd907d68https://doi.org/10.1093/eurheartj/ehab836
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