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March 1, 2026SHILAP Revista de lepidopterologíaOpen Access

Editorial: Exploring key pathways in the progression of gastrointestinal diseases based on metabolic reprogramming and developing drugs targeting metabolism

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Authors

JJJilin JiaZJZimo JiaBYB. Yang

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Overview

This editorial discusses pathways in gastrointestinal diseases and highlights metabolism-targeted treatments, suggesting new therapeutic directions.

Key Points

  • The aim is to explore metabolic reprogramming in gastrointestinal neoplasms and its implications for therapy.
  • Review of published articles in Frontiers in Immunology.
  • Discussion of metabolic alterations in gastrointestinal cancers.
  • Examination of immune suppression and tumor progression related to metabolism.
  • Identified significant metabolic changes, including the Warburg effect and glutamine addiction.
  • Highlighted the role of metabolites in influencing the tumor microenvironment.
  • Suggested that GIPC2 could be both a biomarker and a therapeutic target.

Cite This Study

Jia et al. (2026) studied this question.

synapsesocial.com/papers/69a3d747ec16d51705d2dbf1https://doi.org/10.3389/fimmu.2026.1808165
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