Incidence and Characteristics of HBV Reactivation-Related Events Following HBsAg Seroclearance: Long-Term Follow-up of a Population-Based Cohort in Japan.

Key Points

• To examine the incidence of HBV reactivation after HBsAg seroclearance among a population-based cohort in Japan.
• Long-term follow-up of a population-based cohort
• Monitoring for HBV reactivation-related events
• Assessment of liver disease severity
• Reactivation-related events were rare following HBsAg seroclearance
• Suggests potential for incomplete viral eradication
• Indicates the importance of careful long-term monitoring in at-risk individuals, especially those with advanced liver disease.