What question did this study set out to answer?

The aim is to evaluate endocrine dysfunctions in HIV-infected individuals on ART compared to those not on ART.

Differences in Endocrine Manifestations in HIV-Infected Subjects on Anti-Retroviral Therapy (ART) Versus not on ART

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Finds endocrine dysfunction more prevalent in patients on anti-retroviral therapy, suggesting a need for monitoring.

The aim is to evaluate endocrine dysfunctions in HIV-infected individuals on ART compared to those not on ART.
Assessed 93 HIV-positive subjects for various hormone levels and CD4+ count.
Conducted thyroid function tests measuring TSH and free thyroxine.
Evaluated fasting plasma glucose and other hormone levels including cortisol, testosterone, and vitamin D.
30% of ART subjects showed severe vitamin D deficiency compared to 6% in non-ART subjects.
37.50% of the ART group had secondary hyperparathyroidism versus 12.10% in the non-ART group.
The ART group exhibited higher rates of endocrine dysfunctions, including various thyroid issues and adrenal insufficiencies.

Manna et al. (2026) studied this question.

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