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March 1, 2026Současné problémy v kolejových vozidlech

The role of serum laboratory biomarkers for complicated and uncomplicated appendicitis in adolescents

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Authors

SŞSerkan ŞengülYGYılmaz GülerHÇHasan Çalış

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Overview

Cross-sectional study examines serum biomarkers' ability to distinguish appendicitis severity in adolescents, suggesting diagnostic improvements.

Key Points

  • The study aims to explore whether serum biomarkers can effectively differentiate between complicated and uncomplicated appendicitis in adolescents.
  • Cross-sectional design evaluating adolescents aged 10 to 19 years with acute appendicitis.
  • Patients categorized into negative appendectomy, uncomplicated, and complicated appendicitis groups.
  • Analysis of serum biomarkers including WBC, NEU, LC, NLR, MPV, RDW, CRP, and LoHS using ROC curve and statistical tests.
  • 277 adolescents were included in the study with specific group distributions.
  • Significant differences found in WBC, NEU, LYM, NLR, CRP, and LoHS between groups.
  • Established cut-off values for NLR, WBC, NEU, and CRP to assist in diagnosing appendicitis severity.

Cite This Study

Şengül et al. (2020) studied this question.

synapsesocial.com/papers/69a3d856ec16d51705d2f20chttps://doi.org/10.29271/jcpsp.2020.4.420
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Diagnostic value of basic laboratory parameters in the diagnosis of complicated appendicitis2024 · 1 citations
  2. 2Diagnostic value of laboratory parameters for complicated appendicitis: A two‑center study2024 · 13 citations
  3. 3The diagnostic values of preoperative laboratory markers in children with complicated appendicitis2012 · 41 citations
  4. 4Blood biomarkers to distinguish complicated and uncomplicated appendicitis in pediatric patients2024 · 19 citations
  5. 5Use of Different Haematological Parameter as a Predictor of Complicated Appendicitis2024