PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
March 1, 20260 citationsOpen Access

Therapeutic Potential of Didymocarpus pedicellata in Diabetes Management: Phytochemical and Pharmacological Insights

View Full Paper
PSPanshul SharmaSKShambhu KumarJGJyoti Gupta

Key Points

  • The research aims to uncover the phytochemical and pharmacological properties of Didymocarpus pedicellata for diabetes management.
  • Conducted phytochemical profiling of antidiabetic species in Kenya
  • Identified chemical classes like flavonoids and terpenoids
  • Tested antidiabetic effects using in vitro and in vivo assays
  • Thirteen species showed high antidiabetic effects
  • Inhibition of αglucosidase and αamylase pathways was significant
  • Nine species have yet to be tested for antidiabetic properties

Abstract

ABSTRACT For many years, folk medicines have employed traditional medicinal plants to treat and manage a variety of conditions and diseases, such as diabetes, pain, ulcers, cancer, and wounds. The phytochemical and antidiabetic properties of the widely used antidiabetic medicinal species in Kenya were the main focus of this investigation. The main chemical classes identified by phytochemical profiling of these species were flavonoids and terpenoids, which have been associated with potent biological effects against the diseases indicated above, among other things. However, as the report points out, many natural product isolation studies have only looked at a small number of the twenty-two species that were chosen. Nine antidiabetic species have not yet been tested for their antidiabetic properties, however all thirteen showed high antidiabetic effects through the inhibition of αglucosidase and αamylase, among other pathways. In order to confirm their antidiabetic use and develop new antidiabetic medications, it is imperative to isolate natural compounds from the chosen antidiabetic species that are often used in Kenya and assess their antidiabetic activity both in vitro and in vivo. Keywords: Didymocarpus pedicellata, Diabetes Mellitus, Bioactive Compound, Molecular target in diabetes.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Sharma et al. (2026) studied this question.

synapsesocial.com/papers/69a3d887ec16d51705d2f84chttps://doi.org/10.5281/zenodo.18797293
Ask AI
Helpful
Bookmark
Share
View Full Paper