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December 1, 2026

Comparing the efficacy of chlorhexidine and povidone-iodine for surgical site disinfection: a systematic review and meta-analysis from randomized controlled trials.

Lei Wang Shenghao Xu Q.‐L. Xu Jianlin Xiao

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Key Points

To compare the effectiveness of chlorhexidine and povidone-iodine in preventing surgical site infections (SSIs).
Conducted a systematic review and meta-analysis
Included randomized controlled trials
Compared outcomes of chlorhexidine and povidone-iodine for SSI prevention
Chlorhexidine showed statistical superiority over povidone-iodine in preventing overall and superficial SSIs
No significant differences found in deep or organ/space SSIs
Secondary outcomes like hospital stay, readmission, and reoperation rates were not significantly different

Implication

Systematic review compares chlorhexidine and povidone-iodine effectiveness in preventing surgical site infections, indicating modest benefits for chlorhexidine.

Discussion

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Cite This Study

Wang et al. (2026) studied this question.

synapsesocial.com/papers/69a3d8b8ec16d51705d2fe1b https://doi.org/10.1080/07853890.2026.2634531

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Keep reading

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