Demonstrates improved extraction of polysaccharides and antioxidants in Astragalus hamosus using deep eutectic solvents, suggesting effective methodologies.
In this study, the efficiency of various solvents and techniques was compared for the extraction of polysaccharides and antioxidants from Astragalus hamosus. Among twenty solvents and four extraction techniques, ultrasonic-assisted extraction using choline chloride-urea (a deep eutectic solvent, DES) demonstrated the best performance. Extraction variables were optimized by the response surface methodology (RSM), and Box-Behnken design (BBD). Extraction yield and total carbohydrate content (TCC) were 44.5% and 2.90 mgGlu/gdw, respectively. Rhamnose, mannose and galactose (molar ratio: 0.34:1.18:1.0) were major monosaccharides in the extracted polysaccharides. Six antioxidant assays—total phenolic content (TPC), total flavonoid content (TFC), DPPH assay, ferric-reducing antioxidant power (FRAP), trolox equivalent antioxidant capacity (TEAC), and reducing power assay (RPA)—were used to evaluate antioxidant capacity. Additionally, different extraction methods, including ultrasonic-assisted, microwave-assisted, maceration, and Soxhlet extractions were compared.
No takes yet. Share an insight, caveat, or question.
Tabaraki et al. (2025) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: