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Synapse
March 1, 20261 citations

Transdermal Delivery of Lornoxicam via Transethosomal Gel as a Novel Strategy for Management of Rheumatoid Arthritis.

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AMAyesha MuneerSSShefaat Ullah ShahRMRashna Mirza

Key Points

  • This research aims to explore a new gel formulation for effective transdermal delivery of lornoxicam in managing rheumatoid arthritis.
  • Development of LOR-TES gel for transdermal application
  • Evaluation of drug delivery efficiency and skin permeation
  • Assessment of sustained release properties
  • LOR-TES gel shows enhanced transdermal drug delivery compared to conventional methods
  • The formulation provides sustained release of lornoxicam
  • Improved skin permeation leads to better management of rheumatoid arthritis symptoms.

Abstract

The developed LOR-TES gel enhanced transdermal drug delivery, offering sustained release and improved permeation. It presents a promising strategy for effective management of rheumatoid arthritis through the transdermal route.

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Cite This Study

Muneer et al. (2026) studied this question.

synapsesocial.com/papers/69a3d8e7ec16d51705d302a1https://doi.org/10.1080/03639045.2026.2637594
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Rheumatoid Arthritis: Pathogenic Roles of Diverse Immune Cells2022 · 596 citations
  2. 2Brain-Targeted Polysorbate 80-Emulsified Donepezil Drug-Loaded Nanoparticles for Neuroprotection2021 · 33 citations
  3. 3Lipid vesicular systems: Formulation optimization and ex vivo comparative study2014 · 13 citations
  4. 4Lornoxicam pharmacokinetics in relation to cytochrome P450 2C9 genotype2004 · 51 citations
  5. 5Formulation Optimization and In-vitro and In-vivo Evaluation of Lornoxicam Ethosomal Gels with Penetration Enhancers2017 · 14 citations