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March 2, 2026SHILAP Revista de lepidopterologíaOpen Access

Tumor-infiltrating lymphocyte therapy in triple-negative breast cancer: from mechanistic exploration to clinical translation

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Authors

YWYongxi WangZZZhe ZhangZCZhuo Chen

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Overview

Review highlights tumor-infiltrating lymphocyte therapy efficacy in triple-negative breast cancer, suggesting novel treatment paths.

Key Points

  • The aim is to explore the role of tumor-infiltrating lymphocytes in triple-negative breast cancer and their therapeutic potential.
  • Review of current literature on tumor-infiltrating lymphocytes and their correlation with outcomes in TNBC.
  • Analysis of mechanistic insights into TIL therapy.
  • Discussion of clinical trial results involving TIL therapy in solid tumors.
  • Higher levels of tumor-infiltrating lymphocytes are linked to better outcomes in early-stage TNBC.
  • Clinical trials indicate TIL therapy's effectiveness across various solid tumors.
  • Exploration of novel therapeutic strategies is essential for enhancing TNBC management.

Cite This Study

Wang et al. (2026) studied this question.

synapsesocial.com/papers/69a528b3f1e85e5c73bf035ahttps://doi.org/10.3389/fimmu.2026.1741333
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Tumor-Infiltrating Lymphocytes in Triple-Negative Breast Cancer: Prognostic Significance, Predictive Value, and Emerging Directions for Clinical Implementation2026
  2. 2Tumor-infiltrating lymphocytes in triple-negative breast cancer: molecular mechanisms, spatial regulation, and therapeutic implications2026
  3. 3Analysis of tumor-infiltrating lymphocytes as prognostic factor in triple-negative breast cancer: A protocol of systematic review and meta-analysis2026
  4. 4Tumor-Infiltrating Lymphocytes (TILs) in Breast Cancer: Prognostic and Predictive Significance across Molecular Subtypes2024 · 68 citations
  5. 5Immunotherapy in the Treatment of Triple-negative Breast Cancer: the Impact and Potential of the TME2024