Hybrid incompatibilities influence male sterility in Drosophila hybrids, suggesting complex genetic interactions.
Hybrid incompatibilities may result from extensive deregulation of genes related to development, metabolism, and reproduction, possibly combined with the activity of specific TE copies. These findings demonstrate the complexity of regulatory incompatibilities in hybrids and the contribution of persistent deregulated genes and TE dynamics to postzygotic isolation.
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Bodelón et al. (2026) studied this question.
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