FORMULATION AND EVALUATION OF Wrightia tinctoria TOPICAL HERBAL GEL ENRICHED WITH ALOEVERA AND VITAMIN E FOR ANTI BACTERIAL ACTIVITY

The aim of the present study is to formulate and evaluate a topical herbal gel that contains Wrightia tinctoria leaf extract. The ethanolic extract of Wrightia tinctoria leaf extract was used to create a gel formulation in different concentrations (0.5, 1, 1.5, and 2%). Topical anti-bacterial activity of gel was also assessed. Gel was prepared using Carbopol 934 (0.5% w/v), tinctoria leaf extract , ethanol, vitamin E, aloe vera, propylene glycol , methyl paraben, ,glycerine, tri-ethanolamine, hydroxy propyl methyl cellulose, rose oil and the necessary amount of distilled water. Wrightia tinctoria extract as the main active ingredient, along with Aloe vera and Vitamin E due to their known antibacterial, anti-inflammatory, soothing, antioxidant, and skin-protective properties. The prepared formulations were assessed for their physical qualities, pH, viscosity, spreadability, extrudability and anti-bacterial activity. The findings suggested that gel compositions were good in terms of appearance and uniformity.